Basic Information
VIS ID
TVIS30013990
Fusion event
HIV-YTHDF3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
64104217/63191659 (Hg38)
End
64104217/63191659 (Hg38)
Orient
+
Location type
Intronic
Target gene
YTHDF3
miRNAs that regulate target gene
hsa-mir-595 ; hsa-mir-513c-5p ; hsa-mir-514b-5p ; hsa-mir-6513-3p ; hsa-mir-124-5p ; hsa-mir-4311 ; hsa-mir-4255 ; hsa-mir-3609 ; hsa-mir-548ah-5p ; hsa-mir-4632-5p ; hsa-mir-4709-3p ; hsa-mir-4436b-3p ; hsa-mir-4796-3p ; hsa-mir-5010-3p ; hsa-mir-6735-5p ; hsa-mir-6879-5p ; hsa-mir-7843-5p ; hsa-mir-539-5p ; hsa-mir-4496 ; hsa-mir-4282 ; hsa-mir-3152-3p ; hsa-mir-6879-3p ; hsa-mir-5096 ; hsa-mir-6802-3p ; hsa-mir-3620-3p ; hsa-mir-6865-3p ; hsa-mir-137
Nearest miRNA
hsa-mir-124-1/Upstream/1476800; hsa-mir-10400/Downstream/1187490;
Nearest TSS
ENST00000518652/Upstream/4129; ENST00000569835/Downstream/24322;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/22452, chr8-CpG: 109/Downstream/1177687
Upstream sequence
TTTCTGTACTTAATGTTTTTAGAAACTTTATATCTTTTTTCTTCtaaaaaaaattaaatataataaaattGTaaatttccttgaccagccagtttatagt
Downstream sequence
caagccctctctctccctctcattactgaaccactgattggttgtttgtccctataagacattttccatattgtcataattgaaattatgtactatatga
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate