Basic Information
VIS ID
TVIS30013999
Fusion event
HIV-GLCCI1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p21.3
Reference genome
GRCh37/hg19
Start
8022015/7982384 (Hg38)
End
8022015/7982384 (Hg38)
Orient
+
Location type
Intronic
Target gene
GLCCI1
miRNAs that regulate target gene
hsa-mir-21-5p ; hsa-mir-335-5p ; hsa-mir-192-5p ; hsa-mir-550b-2-5p ; hsa-mir-5590-5p ; hsa-mir-1227-3p ; hsa-mir-5580-3p ; hsa-mir-8485 ; hsa-mir-4443 ; hsa-mir-650 ; hsa-mir-7847-3p ; hsa-mir-3612 ; hsa-mir-3941 ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p ; hsa-mir-129-5p ; hsa-mir-153-5p ; hsa-mir-297 ; hsa-mir-3149 ; hsa-mir-33a-5p ; hsa-mir-33b-5p ; hsa-mir-3680-3p ; hsa-mir-450b-5p ; hsa-mir-507 ; hsa-mir-557 ; hsa-mir-675-3p
Nearest miRNA
hsa-mir-339/Upstream/915339; hsa-mir-10399/Downstream/10144836;
Nearest TSS
ENST00000635602/Upstream/11932; ENST00000496617/Downstream/21513;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/12520, chr7-CpG: 118/Downstream/279017
Upstream sequence
GAGTGCCAGGAAAGCAGGTGTTCAGATTTTGTGTCAGAGCTTGTTATTTTTTTCATACTAGGATTATCACCCTTTAGATTATTAATACTGATTATATAGG
Downstream sequence
GCACTGAAAGAACTCAACATTTTCTTTGTATACTTTTTTACACTAATGTTATTGTTATACATAAATGGTAGTCTTCATTTTTGAAGTCTTTCACAttttt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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