Basic Information
VIS ID
TVIS30014001
Fusion event
HIV-PCM1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
p22
Reference genome
GRCh37/hg19
Start
17822505/17964996 (Hg38)
End
17822505/17964996 (Hg38)
Orient
+
Location type
Intronic
Target gene
PCM1
miRNAs that regulate target gene
hsa-mir-33a-5p ; hsa-mir-129-5p ; hsa-mir-8055
Nearest miRNA
hsa-mir-124-1/Upstream/283339; hsa-mir-10400/Downstream/4279970;
Nearest TSS
ENST00000518652/Upstream/2043; ENST00000523540/Downstream/4427;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/41233, chr8-CpG: 103/Downstream/118794
Upstream sequence
tactcagagttagtgcagacccctcaagttaaggggctcagttcagtaagactgccctcacctcagacttcaatttcaactgcttggtccccacgttacc
Downstream sequence
cacacttctgtgcaacatggctagaaatttgggagttcttacaatccccttcaggtttatttgctagaacaactcacgaaatacaggaaaagacttactt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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