Basic Information
VIS ID
TVIS30014003
Fusion event
HIV-KPNA3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr13
Cytoband
q14.2
Reference genome
GRCh37/hg19
Start
50319967/49745831 (Hg38)
End
50319967/49745831 (Hg38)
Orient
-
Location type
Intronic
Target gene
KPNA3
miRNAs that regulate target gene
hsa-mir-16-5p ; hsa-mir-92a-3p ; hsa-mir-219a-1-3p ; hsa-mir-1199-5p ; hsa-mir-6751-3p ; hsa-mir-4303 ; hsa-mir-3200-5p ; hsa-mir-548c-3p ; hsa-mir-455-5p ; hsa-mir-599 ; hsa-mir-374a-3p ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-4524b-5p ; hsa-mir-4524a-5p ; hsa-mir-524-5p ; hsa-mir-520d-5p ; hsa-mir-1279 ; hsa-mir-409-5p ; hsa-mir-487a-3p ; hsa-mir-154-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-646 ; hsa-mir-15a-5p ; hsa-mir-15b-5p ; hsa-mir-424-5p ; hsa-mir-497-5p ; hsa-mir-195-5p ; hsa-mir-6838-5p ; hsa-mir-503-5p ; hsa-mir-1244 ; hsa-mir-676-5p
Nearest miRNA
hsa-mir-2276/Upstream/5549631; hsa-mir-1267/Downstream/250584;
Nearest TSS
ENST00000623511/Upstream/40079; ENST00000615830/Downstream/47055;
Nearest CpG islands
None/Target, chr13-CpG: 551/Upstream/54111, chr13-CpG: 124/Downstream/46093
Upstream sequence
CAAAGATCTGAAATAAGttttaaatttattttttaaaaGATATATGTATAggccgggcacggtggctcacgcctgtaatcccagcactttgggaggctga
Downstream sequence
ggcgggcagatcacgaggtcaggagatcgagaccatcctggctaacacggtgaaaccccatctctactaaaaatacaaaaaattagccggacgaggtggt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate