Basic Information
VIS ID
TVIS30014014
Fusion event
HIV-GSPT1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p13.13
Reference genome
GRCh37/hg19
Start
11999381/11905524 (Hg38)
End
11999381/11905524 (Hg38)
Orient
+
Location type
Intronic
Target gene
GSPT1
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-361-5p ; hsa-mir-183-5p ; hsa-mir-383-3p ; hsa-mir-873-5p ; hsa-mir-218-5p ; hsa-mir-1273e ; hsa-mir-7160-5p ; hsa-mir-1827 ; hsa-mir-4649-3p ; hsa-mir-940 ; hsa-mir-6893-5p ; hsa-mir-6808-5p ; hsa-mir-302f ; hsa-mir-6864-3p ; hsa-mir-3672 ; hsa-mir-6801-5p ; hsa-mir-769-5p ; hsa-mir-4786-5p ; hsa-mir-6500-3p ; hsa-mir-3614-5p ; hsa-mir-4275 ; hsa-mir-205-3p ; hsa-mir-576-3p ; hsa-mir-5197-5p ; hsa-mir-374c-3p ; hsa-mir-8055 ; hsa-mir-7977 ; hsa-mir-6884-5p ; hsa-mir-485-5p
Nearest miRNA
hsa-mir-1225/Upstream/598997; hsa-mir-11401/Downstream/814797;
Nearest TSS
ENST00000527434/Upstream/7636; ENST00000562802/Downstream/2684;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/53864, chr16-CpG: 129/Downstream/9499
Upstream sequence
AGTACACACTTGCCTACCTAATCCCCCATTTCTATCCCATTCCCTGTCCATCCCCTACCCTGAAGGGCTAATGATCACTCCCCTAGGACATGACACCTCT
Downstream sequence
TTAAATTAGAGGCACACATGGGgaccaggtgcagtggctcacacctgtacctgtaatcccagcactttgggaggccaaggcgggcagataacttgaggtc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate