Basic Information
VIS ID
TVIS30014016
Fusion event
HIV-LPIN2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr18
Cytoband
p11.31
Reference genome
GRCh37/hg19
Start
2951779/2951781 (Hg38)
End
2951779/2951781 (Hg38)
Orient
+
Location type
Intronic
Target gene
LPIN2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-769-5p
Nearest miRNA
hsa-mir-8078/Upstream/2839442; hsa-mir-1-2/Downstream/933572;
Nearest TSS
ENST00000575820/Upstream/3440; ENST00000582591/Downstream/15237;
Nearest CpG islands
None/Target, chr18-CpG: 67/Upstream/38472, chr18-CpG: 105/Downstream/60768
Upstream sequence
CAGCAACAAAAATCTCAGGAGGTGTTACAAAGGACTCTCTCAAGAACTCACACAGAACATTCAGAACAGGAAAAAGCAGAAGGCAGAGATTAAGGACACT
Downstream sequence
ACATCAGACAAAGGGCAGCAGGACAGGTGAGTGACGCGAGGATGCAGTGATACAGAGCGGCCAATGCTTATGTTTTGCCAAATTAATTGGAGAAAGGCAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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