Basic Information
VIS ID
TVIS30014018
Fusion event
HIV-JAML integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
118093343/118222628 (Hg38)
End
118093343/118222628 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11B
Target gene
JAML
miRNAs that regulate target gene
hsa-mir-1238-3p ; hsa-mir-670-3p ; hsa-mir-6749-3p ; hsa-mir-6792-3p ; hsa-mir-4691-5p ; hsa-mir-3124-3p ; hsa-mir-665 ; hsa-mir-4328 ; hsa-mir-873-5p
Nearest miRNA
hsa-mir-10392/Upstream/4772540; hsa-let-7a-2/Downstream/421372;
Nearest TSS
ENST00000527297/Upstream/7737; ENST00000529713/Downstream/1459;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/69149, chr11-CpG: 22/Downstream/136821
Upstream sequence
atttatataaaagagctctaattaattggcttaaagaaactaaaatcaaacattttatcagaaaaaattgaaactttaatctcttttaggtcacgtgact
Downstream sequence
ctaatgatttttaaacataaagacagtgtaaataacataaaaaataaagacagtgtaagtaaagaatgtgttttggtgggaggttataagaaggcgtgtg
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate