Basic Information
VIS ID
TVIS30014020
Fusion event
HIV-CREG1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
167512188/167542951 (Hg38)
End
167512188/167542951 (Hg38)
Orient
+
Location type
Intronic
Target gene
CREG1
miRNAs that regulate target gene
hsa-mir-31-5p ; hsa-mir-26b-5p ; hsa-mir-941 ; hsa-mir-30e-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-30b-5p ; hsa-mir-30a-5p ; hsa-mir-195-5p ; hsa-mir-16-5p ; hsa-mir-15a-5p ; hsa-mir-15b-5p
Nearest miRNA
hsa-mir-101-1/Upstream/1388153; hsa-mir-1182/Downstream/455709;
Nearest TSS
ENST00000473358/Upstream/24341; ENST00000461790/Downstream/3229;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/86972, chr1-CpG: 82/Downstream/10281
Upstream sequence
GGAAATATCCGGATGTGCGCCAGAGGAGATAAAATGAGGCTTAGCACAAACATGCTGCTGCCCAGACTTAACAGTGGTCAAAAGCAATGCTTATGCTTAT
Downstream sequence
AAGAACTGCTTGTTgggcgggcgcggtggctcacacctataatcccagcattttgggaggccgaggcgggcagatcacgaggtcaggagattgagaccat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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