Basic Information
VIS ID
TVIS30014028
Fusion event
HIV-TCF20 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.2
Reference genome
GRCh37/hg19
Start
42627211/42231205 (Hg38)
End
42627211/42231205 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
TCF20
miRNAs that regulate target gene
hsa-mir-149-5p ; hsa-mir-205-5p ; hsa-mir-1247-5p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-8485 ; hsa-mir-433-3p ; hsa-mir-7154-5p ; hsa-mir-623 ; hsa-mir-6780b-3p ; hsa-mir-4780 ; hsa-mir-6729-3p ; hsa-mir-6847-5p ; hsa-mir-6866-3p ; hsa-mir-188-5p ; hsa-mir-1178-5p ; hsa-mir-4779
Nearest miRNA
hsa-mir-1281/Upstream/307908; hsa-let-7a-3/Downstream/2969749;
Nearest TSS
ENST00000624155/Upstream/15763; ENST00000332965/Downstream/38548;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/78008, chr22-CpG: 180/Downstream/38241
Upstream sequence
gagctgagactgcaccattccactccaacctgggcgacacagcaagactctgtctcaaataatgataataaatagaaaaaaaagcttataaagtggctag
Downstream sequence
gcctggtggctcacacctacaattccagaacttttgggaggcagaggagaaaggattgcttgatgccaggagtttgagaccagcctgggcaacatagcat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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