Basic Information
VIS ID
TVIS30014033
Fusion event
HIV-PLAAT4 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q12.3
Reference genome
GRCh37/hg19
Start
63308510/63541038 (Hg38)
End
63308510/63541038 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
PLAAT4
miRNAs that regulate target gene
hsa-mir-30e-3p
Nearest miRNA
hsa-mir-129-2/Upstream/748267; hsa-let-7a-2/Downstream/800811;
Nearest TSS
ENST00000527297/Upstream/2642; ENST00000542805/Downstream/22345;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/49706, chr11-CpG: 73/Downstream/72633
Nearest cancer related gene
PLAAT4(TSG, No orient, 0)
Upstream sequence
TGTTCTCTTTTCACCAAGCATTTACATTGTCACTGGACAAAAACCATTCCCATCACTATCAGGGCAAGACATTTGCATCTTATCAGTTTTCTCCAAGCCA
Downstream sequence
TCATCTCCCAGGCAGGATTGTAAAAATGTCTGAATTGATGGAAAATAGTAAATCAAGCCCACTTAATCCAGATGATCCTCAGGGACCTTGTAAGACAAAG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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