Basic Information
VIS ID
TVIS30014043
Fusion event
HIV-RABL6 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr9
Cytoband
q34.3
Reference genome
GRCh37/hg19
Start
139709512/136815060 (Hg38)
End
139709512/136815060 (Hg38)
Orient
+
Location type
Intronic
Target gene
RABL6
miRNAs that regulate target gene
hsa-mir-1226-3p ; hsa-mir-425-5p ; hsa-mir-484 ; hsa-mir-191-5p ; hsa-mir-222-3p ; hsa-mir-10a-5p ; hsa-let-7e-5p
Nearest miRNA
hsa-let-7a-1/Upstream/68090; hsa-mir-3621/Downstream/15897;
Nearest TSS
ENST00000422679/Upstream/6212; ENST00000436380/Downstream/6269;
Nearest CpG islands
None/Target, chr9-CpG: 64/Upstream/6289, chr9-CpG: 86/Downstream/6151
Upstream sequence
GCCATCCTCTTGGCTTTCCCAGGAACAGCATTTGTAGAAGCTTTCTTTCCTTTGGCTGGTGTTGTTTCCATAGGTGCTGCTTCAGAGCCATCTTCCTCAG
Downstream sequence
CATCGTCCTCATCGTCCTCGTCCTCATCCCCTGAGGCAGGGGCACCCGCTGCTGCCTTCATCACTGCTGGTTCAGAGTCATCCTCCTCCTCATCGCTGTC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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