Basic Information
VIS ID
TVIS30014048
Fusion event
HIV-MRPL14 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
44091987/44124250 (Hg38)
End
44091987/44124250 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
MRPL14
miRNAs that regulate target gene
hsa-mir-324-5p
Nearest miRNA
hsa-mir-10398/Upstream/689630; hsa-mir-10524/Downstream/129956;
Nearest TSS
ENST00000381078/Upstream/49598; ENST00000532634/Downstream/2664;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/47439, chr6-CpG: 137/Downstream/2721
Upstream sequence
GGCTCCAGGTTTATTAAGATGTCAGATAGGCAGGAGAGTAGTGTGAAAAAGTTAAAGAATGGGGGTGGGAGGGTGCTGCTGATGGAAAGCATATATCTCT
Downstream sequence
TTCACTCCATCCTCCCCTTCTCTCACACCAAGTCTGTGGCCCTGGAATCACCTGTCTGGGTCTCAACGACTCTCTGTCAAGCAGAGATCATATTGGGAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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