Basic Information
VIS ID
TVIS30014053
Fusion event
HIV-PEAK1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
77648282/77355940 (Hg38)
End
77648282/77355940 (Hg38)
Orient
+
Location type
Intronic
Target gene
PEAK1
miRNAs that regulate target gene
hsa-mir-183-5p ; hsa-mir-3941 ; hsa-mir-8485 ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-3190-3p ; hsa-mir-3202 ; hsa-mir-4533 ; hsa-mir-1252-5p ; hsa-mir-223-5p ; hsa-mir-603 ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-574-3p ; hsa-mir-769-3p ; hsa-mir-450b-3p ; hsa-mir-638 ; hsa-mir-4713-3p ; hsa-mir-627-3p ; hsa-mir-6845-3p ; hsa-mir-2392 ; hsa-mir-32-5p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-1251-5p ; hsa-mir-1273h-5p ; hsa-mir-149-3p ; hsa-mir-1827 ; hsa-mir-2682-5p ; hsa-mir-30b-3p ; hsa-mir-3192-5p ; hsa-mir-34b-5p ; hsa-mir-3612 ; hsa-mir-3689a-3p ; hsa-mir-3689b-3p ; hsa-mir-3689c ; hsa-mir-449c-5p ; hsa-mir-4728-5p ; hsa-mir-517-5p ; hsa-mir-5197-3p ; hsa-mir-6508-5p ; hsa-mir-650 ; hsa-mir-6779-5p ; hsa-mir-6780a-5p ; hsa-mir-6785-5p ; hsa-mir-6799-5p ; hsa-mir-6817-3p ; hsa-mir-6873-3p ; hsa-mir-6883-5p ; hsa-mir-6895-3p ; hsa-mir-7106-5p ; hsa-mir-7110-3p ; hsa-mir-8067 ; hsa-mir-511-3p
Nearest miRNA
hsa-mir-10393/Upstream/1593625; hsa-mir-11181/Downstream/1853848;
Nearest TSS
ENST00000557528/Upstream/9309; ENST00000560986/Downstream/64154;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/284722, chr15-CpG: 100/Downstream/63343
Upstream sequence
CCAGAATATCAGCCCTGGAAAAGTTACAGCCCTGGAAAAATGGAGAGAACTCAGAAAAACCCCTGGGTTGACTAGGACCCCTGTGTGTGGAATGGTGGCT
Downstream sequence
TAGGCCTGAGACAAGAGGCAGTCCAGCAAAGCTGTGGgataacaaacgagaaaaagaactactaaagttctattttgcttcTCTTGTATTCCAGTGCCCA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate