Basic Information
VIS ID
TVIS30014063
Fusion event
HIV-GGA1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
38011245/37615238 (Hg38)
End
38011245/37615238 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA22A
Target gene
GGA1
miRNAs that regulate target gene
hsa-mir-320a ; hsa-mir-136-5p ; hsa-mir-6881-3p ; hsa-mir-6780a-3p ; hsa-mir-7111-3p ; hsa-mir-210-5p ; hsa-mir-4749-3p ; hsa-mir-324-3p ; hsa-mir-1913 ; hsa-mir-3667-3p ; hsa-mir-6769b-3p ; hsa-mir-4723-3p ; hsa-mir-3183 ; hsa-mir-6756-3p ; hsa-mir-3127-3p
Nearest miRNA
hsa-mir-1286/Upstream/1328331; hsa-let-7a-3/Downstream/229034;
Nearest TSS
ENST00000624155/Upstream/1105; ENST00000491295/Downstream/3165;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/5974, chr22-CpG: 51/Downstream/24105
Upstream sequence
tcatctcttaaaaaataaaaaaaTAggccaggcatggtggctcacgcctgtaatcccagcactttgggaggccaaggcaggtggatcacctgaggttggg
Downstream sequence
agttcaagaccagccttaccaacatagagaaatcccatctctactaaaaatacaaaaaaaattagccgggcatggtggtgcatgcctgtaatcccagcta
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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