Basic Information
VIS ID
TVIS30014080
Fusion event
HIV-NCOA1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p23.3
Reference genome
GRCh37/hg19
Start
24949995/24727126 (Hg38)
End
24949995/24727126 (Hg38)
Orient
-
Location type
Intronic
Target gene
NCOA1
miRNAs that regulate target gene
hsa-mir-22-3p ; hsa-let-7d-5p ; hsa-mir-34a-5p ; hsa-mir-548e-5p ; hsa-mir-105-5p ; hsa-mir-129-5p ; hsa-mir-3158-5p ; hsa-mir-3185 ; hsa-mir-4461 ; hsa-mir-519d-5p ; hsa-mir-604 ; hsa-mir-647 ; hsa-mir-6762-3p ; hsa-mir-6772-3p ; hsa-mir-6885-3p ; hsa-mir-7853-5p ; hsa-mir-889-5p
Nearest miRNA
hsa-mir-3125/Upstream/5378621; hsa-mir-10b/Downstream/601514;
Nearest TSS
ENST00000437798/Upstream/19399; ENST00000493773/Downstream/40645;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/234827, chr2-CpG: 68/Downstream/65884
Upstream sequence
actcaggaggctgaggcaggagaattgcttgaacccaggaggtggaggttgcagtgagccaagattgcgccattgcactccagcctgggcaacaagagtg
Downstream sequence
aaactctgtctcaaaaaaaaaaaaaaaaaaaaaaaaGGGTGGCGGGGACAAGGGAAAGACACTGAATTAAACAGATTTATTGACTGCATGACCACAAGGC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate