Basic Information
VIS ID
TVIS30014082
Fusion event
HIV-EIF2B3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.1
Reference genome
GRCh37/hg19
Start
45379789/44914117 (Hg38)
End
45379789/44914117 (Hg38)
Orient
+
Location type
Intronic
Target gene
EIF2B3
miRNAs that regulate target gene
hsa-let-7b-5p ; hsa-mir-615-3p ; hsa-mir-320a
Nearest miRNA
hsa-mir-12136/Upstream/368565; hsa-mir-101-1/Downstream/6145720;
Nearest TSS
ENST00000473358/Upstream/38495; ENST00000461035/Downstream/12538;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/70630, chr1-CpG: 38/Downstream/72233
Upstream sequence
atgtagtctcaggatgttgcccaggctggtctcaaactcctggcctcaagttattctcttgccttggtctctcaaagtggacattagtggtgtgagccac
Downstream sequence
cgcacccagccTTACTTGCTTTTAAAACTTTTTAAATTGGGAAtttttttttttttttttgaggcagagttccactcttgttgcccaagctggaatgcaa
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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