Basic Information
VIS ID
TVIS30014084
Fusion event
HIV-CHD2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr15
Cytoband
q26.1
Reference genome
GRCh37/hg19
Start
93518673/92975443 (Hg38)
End
93518673/92975443 (Hg38)
Orient
-
Location type
Intronic
Target gene
CHD2
miRNAs that regulate target gene
hsa-mir-450a-5p ; hsa-mir-196b-5p ; hsa-mir-378a-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-10393/Upstream/70968; hsa-mir-1302-10/Downstream/3357818;
Nearest TSS
ENST00000557528/Upstream/714; ENST00000627185/Downstream/9016;
Nearest CpG islands
None/Target, chr15-CpG: 55/Upstream/70850, chr15-CpG: 34/Downstream/69429
Upstream sequence
TCTGATACAGTGTGGCTTAATGTTCTTGCTCTCGCTAACAGCAACATTTTACAATCAGTGTCGAGCTTGGATTTGGCATTATGAAGTATTTTGTTTGGGG
Downstream sequence
GGCACATATAGAAGAGCTACTTAGGATGAAATAGAAGGTATGACAACATTGTAGTTTGTGCATATCAAATCATCAGATGCCATGGGATTTGAGAGAAGTG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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