Basic Information
VIS ID
TVIS30014085
Fusion event
HIV-UTRN integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
q24.2
Reference genome
GRCh37/hg19
Start
144844822/144523686 (Hg38)
End
144844822/144523686 (Hg38)
Orient
-
Location type
Intronic
Target gene
UTRN
miRNAs that regulate target gene
hsa-mir-206 ; hsa-mir-1-3p ; hsa-mir-21-5p ; hsa-mir-455-3p ; hsa-mir-505-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-let-7b-5p ; hsa-mir-3136-3p ; hsa-mir-4313 ; hsa-mir-26a-2-3p ; hsa-mir-26a-1-3p ; hsa-mir-1915-5p ; hsa-mir-6793-3p ; hsa-mir-4714-3p ; hsa-mir-203b-5p ; hsa-mir-3691-3p ; hsa-mir-556-3p ; hsa-mir-6718-5p ; hsa-mir-6801-5p
Nearest miRNA
hsa-mir-10398/Upstream/3839803; hsa-mir-1202/Downstream/6578989;
Nearest TSS
ENST00000381078/Upstream/179585; ENST00000367525/Downstream/59524;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/236542, chr6-CpG: 132/Downstream/1211074
Upstream sequence
aggtgtgagccactgcacccggccTTATGCCCTGTTTAATAAATTGTGATGAGTATAGTTCCTTAAAGGAGGAATGTGATCATGTATAGATGACCATTTA
Downstream sequence
TAACATAATATCTTAATGATATGGAAGCACTTCTAATTTTTAGTGTCTAAATAGTGTCCATTCTCTTTAAAAAAACTAAAGAAATTTTTCATTAATGTTC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate