Basic Information
VIS ID
TVIS30014091
Fusion event
HIV-GPATCH2L integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
76656050/76189707 (Hg38)
End
76656050/76189707 (Hg38)
Orient
-
Location type
Intronic
Target gene
GPATCH2L
miRNAs that regulate target gene
hsa-mir-629-3p ; hsa-mir-519e-5p ; hsa-mir-515-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-767-5p ; hsa-mir-4793-3p ; hsa-mir-3130-3p
Nearest miRNA
hsa-mir-208a/Upstream/1709503; hsa-mir-1185-1/Downstream/1076511;
Nearest TSS
ENST00000550708/Upstream/8892; ENST00000556372/Downstream/6201;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/37598, chr14-CpG: 32/Downstream/163095
Upstream sequence
ttaggtttttccaaatataagttcatatcatctacaaacaaggatactttgatgtcttccttttcggtttggatgccctttatttctttctcttgtctga
Downstream sequence
ttactctagctaggacttccagtcctaaattgagtaacagtggtgaaggtgggcatccttatcatgttccatatcttagaagagaggcctttcagttttt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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