Basic Information
VIS ID
TVIS30014110
Fusion event
HIV-SAE1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.32
Reference genome
GRCh37/hg19
Start
47701178/47197921 (Hg38)
End
47701178/47197921 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
SAE1
miRNAs that regulate target gene
hsa-mir-1229-3p ; hsa-mir-615-3p ; hsa-mir-324-3p ; hsa-mir-151a-3p ; hsa-mir-30a-5p ; hsa-mir-30c-5p ; hsa-mir-30d-5p ; hsa-mir-203a-5p ; hsa-mir-30b-5p ; hsa-mir-30e-5p ; hsa-mir-4266 ; hsa-mir-4695-5p ; hsa-mir-4779 ; hsa-mir-1273g-5p ; hsa-mir-6816-3p ; hsa-mir-3651 ; hsa-mir-6779-3p ; hsa-mir-7976 ; hsa-mir-651-5p ; hsa-mir-299-5p ; hsa-mir-103b ; hsa-mir-129-2-3p ; hsa-mir-129-1-3p ; hsa-mir-4687-5p
Nearest miRNA
hsa-mir-10395/Upstream/488567; hsa-let-7e/Downstream/29021;
Nearest TSS
ENST00000633603/Upstream/67026; ENST00000601154/Downstream/24647;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/66814, chr19-CpG: 88/Downstream/28139
Upstream sequence
agtgtgtgaccttgtgtcgtacgtgtgcaggtacaactgcaggataattaggaggaagggagttgctgggtcagaaggttgtaatttatcatttggtcag
Downstream sequence
cattgccaccttgcctccattggtatcctatcaattcatacccccagcagcaaAACCACCCATGTTCCCAGCATCCTCTCACTTGGACACTCCATGCTTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate