Basic Information
VIS ID
TVIS30014130
Fusion event
HIV-ABCE1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
146044130/145122978 (Hg38)
End
146044130/145122978 (Hg38)
Orient
+
Location type
Intronic
Target gene
ABCE1
miRNAs that regulate target gene
hsa-mir-203a-3p ; hsa-mir-24-3p ; hsa-mir-30c-5p ; hsa-mir-29a-3p ; hsa-mir-29b-3p ; hsa-mir-29c-3p ; hsa-mir-548e-5p ; hsa-mir-6835-3p ; hsa-mir-548x-3p ; hsa-mir-548j-3p ; hsa-mir-548aq-3p ; hsa-mir-548am-3p ; hsa-mir-548aj-3p ; hsa-mir-548ah-3p ; hsa-mir-548ae-3p ; hsa-mir-548z ; hsa-mir-548h-3p ; hsa-mir-548d-3p ; hsa-mir-548bb-3p ; hsa-mir-548ac ; hsa-mir-299-3p
Nearest miRNA
hsa-mir-12113/Upstream/1779443; hsa-mir-1305/Downstream/1285605;
Nearest TSS
ENST00000502981/Upstream/109; ENST00000514168/Downstream/27917;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/24304, chr4-CpG: 143/Downstream/56624
Upstream sequence
ATAGATGGTGGATACACATTGATATCTGTTGGTGGCAAATTGATATACTTTTATTCTGAAGCTTAACTTTGTCAAGATTCATAAATAGAAGAGTTCTATA
Downstream sequence
GTGAAAGTTTATCATTTAAATACTTTTTTATATTAAAAACAGGGAAGTGTTCGCCAGTTACTACATGAAAAGATAAGAGATGCTTATACTCACCCACAAT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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