Basic Information
VIS ID
TVIS30014131
Fusion event
HIV-TPP1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.4
Reference genome
GRCh37/hg19
Start
6637303/6616072 (Hg38)
End
6637303/6616072 (Hg38)
Orient
-
Location type
Exonic
Target gene
TPP1
miRNAs that regulate target gene
hsa-mir-124-3p ; hsa-mir-877-5p ; hsa-mir-7-5p ; hsa-mir-450a-2-3p ; hsa-mir-6516-5p ; hsa-mir-6857-5p ; hsa-mir-6763-5p ; hsa-mir-3150a-3p ; hsa-mir-6810-5p ; hsa-mir-2110 ; hsa-mir-455-3p ; hsa-mir-502-5p ; hsa-mir-4671-3p ; hsa-mir-6780b-5p ; hsa-mir-4725-3p ; hsa-mir-4271 ; hsa-mir-6716-5p ; hsa-mir-6499-3p ; hsa-mir-219a-2-3p ; hsa-mir-219b-3p ; hsa-mir-1915-5p ; hsa-mir-6841-3p ; hsa-mir-6513-3p ; hsa-mir-454-3p ; hsa-mir-4295 ; hsa-mir-3666 ; hsa-mir-301b-3p ; hsa-mir-301a-3p ; hsa-mir-130b-3p ; hsa-mir-130a-3p ; hsa-mir-184 ; hsa-mir-3191-3p ; hsa-mir-451b ; hsa-mir-92b-5p
Nearest miRNA
hsa-mir-210/Upstream/2759931; hsa-let-7a-2/Downstream/618694;
Nearest TSS
ENST00000527297/Upstream/617; ENST00000545572/Downstream/197;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/3516, chr11-CpG: 146/Downstream/13602
Upstream sequence
GTTATACCTGAGTGGTAGGCTAGAGTACTTACCTGGAGGCAGGGAAGGTAGGGCGGAACTGGTGTCTTCCAGAGACAGACCAACACCCGGCCCCACTGTC
Downstream sequence
ACCTGAGAGAGACCAAGTGTAGCATTCATATTAATTGGTTAGGGCTTAGTATGTGGGTTCGGATGTCAGAGGGGAAATTTGTTACTGTAGGAGGTCAGAG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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