Basic Information
VIS ID
TVIS30014133
Fusion event
HIV-OGDH integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
p13
Reference genome
GRCh37/hg19
Start
44668817/44629218 (Hg38)
End
44668817/44629218 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA7D
Target gene
OGDH
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-30a-5p ; hsa-mir-16-5p ; hsa-mir-361-5p ; hsa-mir-552-5p ; hsa-mir-4326 ; hsa-mir-1293 ; hsa-mir-1321 ; hsa-mir-149-3p ; hsa-mir-151a-5p ; hsa-mir-151b ; hsa-mir-1914-3p ; hsa-mir-2278 ; hsa-mir-2467-3p ; hsa-mir-3141 ; hsa-mir-4419a ; hsa-mir-4468 ; hsa-mir-4483 ; hsa-mir-4510 ; hsa-mir-4651 ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-5194 ; hsa-mir-608 ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6738-5p ; hsa-mir-6782-5p ; hsa-mir-6785-5p ; hsa-mir-6873-5p ; hsa-mir-6883-5p ; hsa-mir-891a-3p ; hsa-mir-4712-3p
Nearest miRNA
hsa-mir-1183/Upstream/518306; hsa-mir-10399/Downstream/252530;
Nearest TSS
ENST00000635602/Upstream/22579; ENST00000497326/Downstream/37403;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/21994, chr7-CpG: 131/Downstream/119206
Upstream sequence
AAGACACAGTCAGAGCTAAGTTATCCTTGTTAATGTTTAAGACAAACAGGTAATTGAGAACTGCTAAGCCCCCATGAGTCTGGGTGTTGATCTCATTTTG
Downstream sequence
TTTTGTAGGGACAGGTGCCCACCTACAGCTGTAGCATGGTGTTGAGTTCCTTGTGATGCATCTGCCAGGTTCTGGCCCTGCTGAGGAAGAGCCAGGATTA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate