Basic Information
VIS ID
TVIS30014135
Fusion event
HIV-NSF integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
44764904/46687538 (Hg38)
End
44764904/46687538 (Hg38)
Orient
+
Location type
Intronic
Target gene
NSF
miRNAs that regulate target gene
hsa-mir-215-5p ; hsa-mir-192-5p ; hsa-mir-103a-3p ; hsa-mir-26b-5p ; hsa-mir-16-5p ; hsa-mir-877-3p ; hsa-mir-193b-3p ; hsa-mir-100-5p ; hsa-mir-32-5p ; hsa-mir-92a-3p ; hsa-mir-92b-3p ; hsa-mir-205-5p ; hsa-mir-218-5p
Nearest miRNA
hsa-mir-1180/Upstream/1212103; hsa-mir-10226/Downstream/285479;
Nearest TSS
ENST00000595228/Upstream/63502; ENST00000576346/Downstream/25611;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/96371, chr17-CpG: 42/Downstream/82235
Upstream sequence
AGCTTCCTTATCATACTACAGGGTAATTTCTTTTCTTCACTGTCAGTCTTCCACCCTACATGCAAGCAATAATCAAATCTAGCATTTGCTGTTTGGTCAT
Downstream sequence
CACCACTCCTGTCACCAAAATTCTCATTCTGTTTAGATTCTGCTTGCCTCATTTATGTACCATTATTTGTTTCTCACTGACCTTCCAAGTGCATACTCCT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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