Basic Information
VIS ID
TVIS30014136
Fusion event
HIV-KLHDC7B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr22
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
50988621/50550192 (Hg38)
End
50988621/50550192 (Hg38)
Orient
+
Location type
UTR3
Target gene
KLHDC7B
miRNAs that regulate target gene
hsa-mir-335-5p
Nearest miRNA
hsa-let-7a-3/Upstream/142668;
Nearest TSS
ENST00000624155/Upstream/2159; ENST00000380711/Downstream/6240;
Nearest CpG islands
None/Target, chr22-CpG: 279/Upstream/480, chr22-CpG: 66/Downstream/12012
Upstream sequence
AAAGGTTGTCGATTATTTTGAAGCCCAGACTCCCTCAGCCTCTTTCTGCCCCTCACTCCACACCCAGACTGTTTCCTGACTCAATTCCGTACCTACTTAC
Downstream sequence
AGACCCTCTCAGCTTGCTGACACCCCCCTGTCTGTGGGACTCCCTATTCCCTAGAGCCAGGGACTGATGCGTCTCCACAGACAAGGACTTGGCTCGCTGG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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