Basic Information
VIS ID
TVIS30014142
Fusion event
HIV-NUP133 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q42.13
Reference genome
GRCh37/hg19
Start
229582561/229446814 (Hg38)
End
229582561/229446814 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1H
Target gene
NUP133
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-1303 ; hsa-mir-4309 ; hsa-mir-3198 ; hsa-mir-4294 ; hsa-mir-516b-5p ; hsa-mir-1289 ; hsa-mir-1298-3p ; hsa-mir-3126-3p ; hsa-mir-3120-3p ; hsa-mir-590-3p ; hsa-mir-27b-3p ; hsa-mir-27a-3p
Nearest miRNA
hsa-mir-101-1/Upstream/984662; hsa-mir-1182/Downstream/1573014;
Nearest TSS
ENST00000473358/Upstream/12716; ENST00000417605/Downstream/3937;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/11877, chr1-CpG: 57/Downstream/61152
Upstream sequence
cacagccagactccatctcaaaaaaaaaatttttttttaataaaaaataaaaataaataaataaaaCAAAATCATAGCTTCGAGTCTCGTTTGGCATGAC
Downstream sequence
AAGCCTCACTTCTGCAAAAATAAGGGATGTggccgggcatggtggctcacgtctgtaatcctagcactttgggaggccgaggcaggcagatcacaaggtc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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