Basic Information
VIS ID
TVIS30014149
Fusion event
HIV-PRMT3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
p15.1
Reference genome
GRCh37/hg19
Start
20436103/20414557 (Hg38)
End
20436103/20414557 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA11C ; FRA11I
Target gene
PRMT3
miRNAs that regulate target gene
hsa-mir-361-3p ; hsa-mir-106b-5p ; hsa-mir-1260b ; hsa-mir-5591-3p ; hsa-mir-5698 ; hsa-mir-891a-3p ; hsa-mir-143-5p ; hsa-mir-4430 ; hsa-mir-3652 ; hsa-mir-564 ; hsa-mir-122-5p ; hsa-mir-504-3p ; hsa-mir-3135b ; hsa-mir-6499-3p ; hsa-mir-5693 ; hsa-mir-4482-5p ; hsa-mir-3130-5p ; hsa-mir-1912 ; hsa-mir-1295b-5p ; hsa-mir-5704 ; hsa-mir-1236-3p ; hsa-mir-6515-3p ; hsa-mir-4495 ; hsa-mir-1295b-3p ; hsa-mir-15a-3p ; hsa-mir-4717-5p
Nearest miRNA
hsa-mir-210/Upstream/654474; hsa-let-7a-2/Downstream/3004548;
Nearest TSS
ENST00000527297/Upstream/9111; ENST00000298923/Downstream/184843;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/26322, chr11-CpG: 123/Downstream/182094
Upstream sequence
gctatcatactttgaactctgcagtgaaagatcatttcggcaacataaacttacctaaggatagcaaagctattcagttgccagacagttgtatactgtg
Downstream sequence
tttattaccctcaggaagcgcaggtagcgtctgtttaatatttttaccattattctgggtgcctttggtttctcattgacacagttatggaatagctcat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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