Basic Information
VIS ID
TVIS30014151
Fusion event
HIV-INTS11 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.33
Reference genome
GRCh37/hg19
Start
1252831/1317451 (Hg38)
End
1252831/1317451 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
INTS11
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-let-7b-5p ; hsa-mir-1226-3p ; hsa-mir-320a ; hsa-mir-23b-3p
Nearest miRNA
hsa-mir-12136/Upstream/4885; hsa-mir-101-1/Downstream/22199;
Nearest TSS
ENST00000473358/Upstream/1; ENST00000488011/Downstream/1895;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/4338, chr1-CpG: 18/Downstream/1491
Upstream sequence
accactgcactacagcctgggcaatgagagcgaaactccatctcaaaaaaaaaagaaaaaaaaaaagaaTtcaacagatgaatttaacaccatatgacac
Downstream sequence
ataaccagaagagaatccatgaactgaaagacaccagagggaatatccatcaggaaacaggaaagacaaacagatgacggagtttcaagaggttgaacgt
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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