Basic Information
VIS ID
TVIS30014154
Fusion event
HIV-PELI1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
p14
Reference genome
GRCh37/hg19
Start
64320007/64092873 (Hg38)
End
64320007/64092873 (Hg38)
Orient
+
Location type
UTR3
Fragile sites / regions
FRA2S
Target gene
PELI1
miRNAs that regulate target gene
hsa-mir-155-5p ; hsa-mir-374b-5p ; hsa-mir-340-5p ; hsa-mir-21-5p ; hsa-mir-296-3p ; hsa-mir-106a-5p ; hsa-mir-17-5p ; hsa-mir-374a-5p ; hsa-mir-578 ; hsa-mir-6794-3p ; hsa-mir-668-3p ; hsa-mir-6845-3p ; hsa-mir-4639-3p ; hsa-mir-224-5p ; hsa-mir-548e-5p
Nearest miRNA
hsa-mir-1301/Upstream/1886956; hsa-mir-10b/Downstream/247874;
Nearest TSS
ENST00000437798/Upstream/4627; ENST00000438115/Downstream/50366;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/73114, chr2-CpG: 112/Downstream/50881
Upstream sequence
GTGGAATAGAGTTGTTCACAGTTTTCACTTCTGGTTTCTCATTCTCGATTATGCAAAAATGAACTCACAGAGACGAATTCAATTATGTATTTTGAAAAGT
Downstream sequence
ATTTACTTAGTTTAAATAAATTAATTGCAAATAAAAATTAAGCTACAATATATAGCCTGAATAAAAATGACTAGAACAAATACAACACAGGACTTGCTTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate