Basic Information
VIS ID
TVIS30014169
Fusion event
HIV-HNRNPM integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
p13.2
Reference genome
GRCh37/hg19
Start
8523022/8458138 (Hg38)
End
8523022/8458138 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA19B
Target gene
HNRNPM
miRNAs that regulate target gene
hsa-mir-30a-5p ; hsa-mir-26b-5p ; hsa-let-7f-1-3p ; hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-193b-3p ; hsa-mir-484 ; hsa-mir-331-3p ; hsa-mir-191-5p ; hsa-mir-15b-5p ; hsa-mir-183-5p ; hsa-mir-93-5p ; hsa-mir-92a-3p ; hsa-mir-29a-3p
Nearest miRNA
hsa-mir-1227/Upstream/68758; hsa-let-7e/Downstream/1580216;
Nearest TSS
ENST00000633603/Upstream/13144; ENST00000593293/Downstream/3831;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/12257, chr19-CpG: 60/Downstream/27517
Upstream sequence
TTTTCTGTCATTATAGCACTATCTAATTGCAGCCTCTCAGAACTAAAGTAGCTAGCTTTGAGAGGCCCAAGAGGGGAGCTTTTTTTCTAAGGATACTCCG
Downstream sequence
GGGGGAGATTGTCTCACATGCTCCTCCCTCACTCTTGATCCTCTTCCCCATCTTTCATACCAGCTGCATATTCTCCAGCTTTAATTTTAGCATTTAGCAG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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