Basic Information
VIS ID
TVIS30014184
Fusion event
HIV-DIDO1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
61510042/62878690 (Hg38)
End
61510042/62878690 (Hg38)
Orient
+
Location type
UTR3
Target gene
DIDO1
miRNAs that regulate target gene
hsa-mir-98-5p ; hsa-mir-744-5p ; hsa-mir-93-3p ; hsa-mir-615-3p ; hsa-mir-181b-5p ; hsa-mir-92a-3p ; hsa-mir-3157-5p ; hsa-mir-3941 ; hsa-mir-582-5p ; hsa-mir-466 ; hsa-mir-4672 ; hsa-mir-198 ; hsa-mir-6504-3p ; hsa-mir-144-3p ; hsa-mir-101-3p ; hsa-mir-4801 ; hsa-mir-4731-3p ; hsa-mir-33a-3p ; hsa-mir-409-3p
Nearest miRNA
hsa-mir-1-1/Upstream/313677; hsa-mir-124-3/Downstream/299810;
Nearest TSS
ENST00000382410/Upstream/16927; ENST00000497101/Downstream/35716;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/1365, chr20-CpG: 81/Downstream/492
Nearest cancer related gene
DIDO1(TSG, No orient, 0)
Upstream sequence
ACAATTATACTAGGACAGATGTTGCTTTAAATCATGTTTTGGAAAAAATTGATAAGGTGATATATAAAATCTGAGCACGCTAAGAAATGTGTTTCTGTTT
Downstream sequence
CCCAGTTGAAAATTGTAATTCCAATTTTATGACAAAAGAAAGATGCATTTGTAAGGTTTGTGTTTCTCAAGACTCCAGATACAAGCTACTAAGACTTCTC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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