Basic Information
VIS ID
TVIS30014186
Fusion event
HIV-EIF4G3 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p36.12
Reference genome
GRCh37/hg19
Start
21283078/20956585 (Hg38)
End
21283078/20956585 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA1A
Target gene
EIF4G3
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-24-3p ; hsa-mir-16-5p ; hsa-mir-221-3p ; hsa-mir-17-5p ; hsa-mir-3613-3p ; hsa-mir-543 ; hsa-mir-136-5p ; hsa-mir-377-5p ; hsa-mir-218-5p ; hsa-mir-548c-3p ; hsa-mir-4724-3p ; hsa-mir-6813-3p ; hsa-mir-3200-3p
Nearest miRNA
hsa-mir-12136/Upstream/322797; hsa-mir-101-1/Downstream/31729;
Nearest TSS
ENST00000473358/Upstream/15101; ENST00000416959/Downstream/25860;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/168957, chr1-CpG: 77/Downstream/220037
Upstream sequence
agtgaaggtggtgggaatgagtcaaatgggacttgctgatgtaatgactgtggagagtgaaattaagaggatttaaaggtgagtcctaggcttagaacct
Downstream sequence
cagcaactTAGGTAGACTACAGTATAATTTACaaaaaaaaaaaaaaaaaaaaCAAGGAGAGCACATCAAACACCTGTTGAAATAttttattttattcaat
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate