Basic Information
VIS ID
TVIS30014188
Fusion event
HIV-NSMCE1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
p12.1
Reference genome
GRCh37/hg19
Start
27271539/27260218 (Hg38)
End
27271539/27260218 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA16E
Target gene
NSMCE1
miRNAs that regulate target gene
hsa-mir-8085 ; hsa-mir-6731-5p ; hsa-mir-324-5p ; hsa-mir-7108-3p ; hsa-mir-4258
Nearest miRNA
hsa-mir-1225/Upstream/1234908; hsa-mir-11401/Downstream/1130764;
Nearest TSS
ENST00000527434/Upstream/2067; ENST00000499939/Downstream/7987;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/55861, chr16-CpG: 35/Downstream/8347
Upstream sequence
aagttaactgtataaaacagtaaaaatcagaagaaatgcttctatctttaaaaaaaagtttttaataccacagtaaaaagaatgaggtttttaaaaaact
Downstream sequence
aaatacacaaaaataataacataaatgggaggtgagcaatcactgggattagtgttctaatagccttgtgatggtcaggagtagaagctggacatgaata
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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