Basic Information
VIS ID
TVIS30014191
Fusion event
HIV-PELI2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q22.3
Reference genome
GRCh37/hg19
Start
56658731/56192013 (Hg38)
End
56658731/56192013 (Hg38)
Orient
+
Location type
Intronic
Target gene
PELI2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-151a-5p ; hsa-mir-222-3p ; hsa-mir-498 ; hsa-mir-377-3p ; hsa-mir-362-3p ; hsa-mir-329-3p ; hsa-mir-34b-3p
Nearest miRNA
hsa-mir-208a/Upstream/1313820; hsa-mir-1185-1/Downstream/3454949;
Nearest TSS
ENST00000550708/Upstream/72904; ENST00000612106/Downstream/113825;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/72497, chr14-CpG: 41/Downstream/387741
Upstream sequence
gtgtgatctcggctcactgcaacctctgtcacccagggtcaagtgattcttctgcctcagcctcccaagtagctggaattacaggcacatgccaccaccc
Downstream sequence
ccagccaatttttgtatttttagtagagaccgggtttcgccatgttggccaggctggtcttgaactgctgacctcaagtgatccacctgcctcggcctcc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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