Basic Information
VIS ID
TVIS30014192
Fusion event
HIV-CAPN1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr11
Cytoband
q13.1
Reference genome
GRCh37/hg19
Start
64962022/65194551 (Hg38)
End
64962022/65194551 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA11H
Target gene
CAPN1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-34a-5p ; hsa-mir-140-5p ; hsa-mir-487a-5p ; hsa-mir-487b-5p ; hsa-mir-1205 ; hsa-mir-4460 ; hsa-mir-203b-5p ; hsa-mir-6718-5p ; hsa-mir-6811-5p ; hsa-mir-6511b-5p ; hsa-mir-6809-5p ; hsa-mir-4708-3p ; hsa-mir-17-3p ; hsa-mir-1184 ; hsa-mir-3158-5p ; hsa-mir-4742-5p ; hsa-mir-1249-5p ; hsa-mir-1321 ; hsa-mir-1343-5p ; hsa-mir-140-3p ; hsa-mir-149-3p ; hsa-mir-151a-5p ; hsa-mir-151b ; hsa-mir-3173-3p ; hsa-mir-3177-3p ; hsa-mir-3188 ; hsa-mir-4419a ; hsa-mir-4445-3p ; hsa-mir-4493 ; hsa-mir-4510 ; hsa-mir-4728-5p ; hsa-mir-4739 ; hsa-mir-4747-5p ; hsa-mir-4756-5p ; hsa-mir-4779 ; hsa-mir-5196-5p ; hsa-mir-548al ; hsa-mir-6127 ; hsa-mir-6129 ; hsa-mir-6130 ; hsa-mir-6133 ; hsa-mir-6785-5p ; hsa-mir-6797-5p ; hsa-mir-6883-5p ; hsa-mir-6891-5p ; hsa-mir-7150 ; hsa-mir-939-5p ; hsa-mir-9500
Nearest miRNA
hsa-mir-10392/Upstream/64573; hsa-let-7a-2/Downstream/249907;
Nearest TSS
ENST00000527297/Upstream/6306; ENST00000530495/Downstream/8821;
Nearest CpG islands
None/Target, chr11-CpG: 30/Upstream/9987, chr11-CpG: 26/Downstream/10163
Upstream sequence
gaaaatttgcacttttaatgtgtgaaatttagtggtttttagtgtacccacagcgttgtgtaagcattgccgttatccagagcatttcttcaccgccccc
Downstream sequence
accccgaaaatcccgtaattattggccatcactttctatccctttctccctagcaaccatgaatctactttttgtctctataaatttacctattctggac
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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