Basic Information
VIS ID
TVIS30014200
Fusion event
HIV-FLT3LG integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr19
Cytoband
q13.33
Reference genome
GRCh37/hg19
Start
49986405/49483148 (Hg38)
End
49986405/49483148 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA19A
Target gene
FLT3LG
Nearest miRNA
hsa-mir-10395/Upstream/174280; hsa-let-7e/Downstream/17637;
Nearest TSS
ENST00000633603/Upstream/4231; ENST00000486930/Downstream/4406;
Nearest CpG islands
None/Target, chr19-CpG: 112/Upstream/18554, chr19-CpG: 51/Downstream/4030
Upstream sequence
aatcattcatcattttgggatattttacattcttttgtcatactaagccttcagcatccaacgtatagtttatttatttatttatttttccttttgagat
Downstream sequence
ggattctcgctctgtcacccaggctggagtgcagtggcgcgatctcagctcactgcaacctcggactccctggttcaggcgattctcctgcctcagcctc
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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