Basic Information
VIS ID
TVIS30014202
Fusion event
HIV-MROH1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr8
Cytoband
q24.3
Reference genome
GRCh37/hg19
Start
145254644/144199741 (Hg38)
End
145254644/144199741 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA8D
Target gene
MROH1
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-222-3p ; hsa-mir-1273h-3p ; hsa-mir-3166 ; hsa-mir-3929 ; hsa-mir-4251 ; hsa-mir-4419b ; hsa-mir-4478 ; hsa-mir-4768-3p ; hsa-mir-4771 ; hsa-mir-485-5p ; hsa-mir-6884-5p
Nearest miRNA
hsa-mir-1204/Upstream/119799; hsa-mir-10400/Downstream/62932;
Nearest TSS
ENST00000518652/Upstream/622; ENST00000528664/Downstream/39371;
Nearest CpG islands
None/Target, chr8-CpG: 109/Upstream/13774, chr8-CpG: 41/Downstream/3156
Upstream sequence
CCTATGCCCTGCACAGGCCCTCATAGCCATCCTGGAGGGGCAGCAGATGGTGTGAGGAGGGGTCCTGCTTGCACTTGGGGCTGTCACCCTGCTGgggcca
Downstream sequence
cagcatcaacatctccctggagctggtcaggcaggcggggcctcaggccccccacctacatgagcatctacccttacacaagatccgcaggAGGGGTGTG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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