Basic Information
VIS ID
TVIS30014213
Fusion event
HIV-VDAC1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr5
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
133392949/134057258 (Hg38)
End
133392949/134057258 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA5C
Target gene
VDAC1
miRNAs that regulate target gene
hsa-mir-1301-3p ; hsa-mir-320c ; hsa-mir-877-5p ; hsa-mir-744-5p ; hsa-mir-615-3p ; hsa-mir-320a ; hsa-mir-125b-5p ; hsa-mir-10a-5p ; hsa-mir-197-3p ; hsa-mir-106a-5p ; hsa-mir-29a-3p ; hsa-mir-20a-5p ; hsa-mir-106b-5p ; hsa-mir-93-5p ; hsa-mir-519d-3p ; hsa-mir-20b-5p ; hsa-mir-17-5p ; hsa-mir-7-5p
Nearest miRNA
hsa-mir-10397/Upstream/629552; hsa-mir-103a-1/Downstream/168499;
Nearest TSS
ENST00000502646/Upstream/52111; ENST00000521970/Downstream/57453;
Nearest CpG islands
None/Target, chr5-CpG: 87/Upstream/51440, chr5-CpG: 30/Downstream/13858
Nearby gene
VDAC1(No orient, 52125)
Upstream sequence
accctgtctctactaaaaatataaaattagccaagtgaaggctgggcacggtggctcatgcctgtaatcccagcactctgagaggccaagatgggcatac
Downstream sequence
cacttgaggtcaggagttggagaccagcctggccaatatggtgaaaccccatctctactaaaaatacaaaaattagctggctgtggtggcacacgcctct
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate