Basic Information
VIS ID
TVIS30014214
Fusion event
HIV-GPBP1L1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
p34.1
Reference genome
GRCh37/hg19
Start
46108400/45642728 (Hg38)
End
46108400/45642728 (Hg38)
Orient
+
Location type
Intronic
Target gene
GPBP1L1
miRNAs that regulate target gene
hsa-mir-9-5p ; hsa-mir-32-5p ; hsa-mir-26b-5p ; hsa-mir-1226-3p ; hsa-mir-30e-5p ; hsa-mir-3163 ; hsa-mir-218-5p ; hsa-mir-409-5p ; hsa-mir-487b-5p ; hsa-mir-487a-5p ; hsa-mir-6892-5p ; hsa-mir-664b-5p ; hsa-mir-5580-3p ; hsa-mir-561-3p ; hsa-mir-548at-5p ; hsa-mir-6818-5p ; hsa-mir-297 ; hsa-mir-6790-5p ; hsa-mir-4658 ; hsa-mir-6867-5p ; hsa-mir-223-5p ; hsa-mir-567 ; hsa-mir-3650 ; hsa-mir-609 ; hsa-mir-4455 ; hsa-mir-6772-5p ; hsa-mir-3659 ; hsa-mir-574-5p ; hsa-mir-6776-5p ; hsa-mir-511-3p ; hsa-mir-548c-3p ; hsa-mir-6738-3p ; hsa-mir-544a ; hsa-mir-4490 ; hsa-mir-137 ; hsa-mir-20a-3p ; hsa-mir-92b-3p ; hsa-mir-92a-3p ; hsa-mir-367-3p ; hsa-mir-363-3p ; hsa-mir-25-3p ; hsa-mir-329-5p ; hsa-mir-32-3p ; hsa-mir-4711-5p ; hsa-mir-7112-3p ; hsa-mir-3613-3p ; hsa-mir-4686 ; hsa-mir-548l ; hsa-mir-548n
Nearest miRNA
hsa-mir-12136/Upstream/1097176; hsa-mir-101-1/Downstream/5417109;
Nearest TSS
ENST00000473358/Upstream/7004; ENST00000496366/Downstream/12518;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/19258, chr1-CpG: 116/Downstream/43351
Upstream sequence
GACACTGTATTCAGAAACGTAACAAACAGAAAATATCAAAACACAAAATCAATAGGTATTATGTTAATATTAGGTTCTCCTGAGTTTCATTTCCTTTGAT
Downstream sequence
ATAAGGGATTTCATTTATTTTAAATAAACAGACTAAATGTGCGAATTCCCACTTTCCTATAGGATATGTATGCCAAATAAGGAGGCACTGAAAGTTAGAT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate