Basic Information
VIS ID
TVIS30014220
Fusion event
HIV-PCIF1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr20
Cytoband
q13.12
Reference genome
GRCh37/hg19
Start
44571669/45943030 (Hg38)
End
44571669/45943030 (Hg38)
Orient
+
Location type
Intronic
Target gene
PCIF1
miRNAs that regulate target gene
hsa-let-7a-5p
Nearest miRNA
hsa-mir-103a-2/Upstream/237850; hsa-mir-1-1/Downstream/1223937;
Nearest TSS
ENST00000382410/Upstream/8297; ENST00000479348/Downstream/1977;
Nearest CpG islands
None/Target, chr20-CpG: 39/Upstream/7878, chr20-CpG: 15/Downstream/3152
Upstream sequence
TAAAACTAGTGATTCTTAGAATATATTTTGGGAAATGCAGCCTAGAAGCTTCTGAAGTGGGACTGTGTCTTGCTTACTGCTGAATGCGATGCTTCCTATA
Downstream sequence
CGTGCCAAGCTCCAAGTGGGACTGCTTGATTAAATCCAGGCCTTCAGCAGCTCTCCTGTCCTGCAGGCATTGAGCCTCCACGGGAGTCTTTCAACCGCTG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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