Basic Information
VIS ID
TVIS30014224
Fusion event
HIV-FUT8 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr14
Cytoband
q23.3
Reference genome
GRCh37/hg19
Start
66105461/65638743 (Hg38)
End
66105461/65638743 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA14B
Target gene
FUT8
miRNAs that regulate target gene
hsa-mir-26b-5p ; hsa-mir-34a-5p ; hsa-mir-122-5p ; hsa-mir-26a-5p ; hsa-mir-455-3p
Nearest miRNA
hsa-mir-208a/Upstream/167557; hsa-mir-1185-1/Downstream/1803112;
Nearest TSS
ENST00000550708/Upstream/2226; ENST00000556662/Downstream/365780;
Nearest CpG islands
None/Target, chr14-CpG: 35/Upstream/225091, chr14-CpG: 40/Downstream/374872
Upstream sequence
CAGCTTATGGAACCCCTCACTCCAACACAGGATTTGCCTGATCTCATTTTTCTTTGACAGGACTAATTCGTTAAGATAGATTTAAAGCCAGAATATAACT
Downstream sequence
ATATACGTTATTTATGTGCTTGTATACTGACTCTGAGATCAAATTAATCATCACATATTCTTAGAGTTGTGAATTGTGTTCTACCAAGTAATTCAGATTG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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