Basic Information
VIS ID
TVIS30014230
Fusion event
HIV-INPP4B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr4
Cytoband
q31.21
Reference genome
GRCh37/hg19
Start
143085267/142164114 (Hg38)
End
143085267/142164114 (Hg38)
Orient
+
Location type
Intronic
Target gene
INPP4B
miRNAs that regulate target gene
hsa-mir-222-3p ; hsa-mir-181a-5p ; hsa-mir-765
Nearest miRNA
hsa-mir-12113/Upstream/16656807; hsa-mir-1305/Downstream/1179346;
Nearest TSS
ENST00000502981/Upstream/442332; ENST00000514766/Downstream/141718;
Nearest CpG islands
None/Target, chr4-CpG: 46/Upstream/526944, chr4-CpG: 111/Downstream/681673
Nearest cancer related gene
INPP4B(TSG, No orient, 0)
Upstream sequence
GATCTATTTTATTTTTTCATATTAGAAAATGAAAGAGAAATGTTACCTTAAAAAAACGAAATGTTTTCTAGCCTTCTGACATTTTTCCAATTCATATCCC
Downstream sequence
CATACAACTATTCTTCAAAGCAACACACAGAATTATCTGCAAGTATAAAACTACTAAAAATTACTTCTCCTGGGGATGAATGAAGAGAATTTCTAGTTTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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