Basic Information
VIS ID
TVIS30014232
Fusion event
HIV-FOXP1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr3
Cytoband
p13
Reference genome
GRCh37/hg19
Start
71069621/71020470 (Hg38)
End
71069621/71020470 (Hg38)
Orient
-
Location type
Intronic
Target gene
FOXP1
miRNAs that regulate target gene
hsa-mir-1-3p ; hsa-mir-122-5p ; hsa-mir-34a-5p ; hsa-mir-335-5p ; hsa-mir-33a-5p ; hsa-mir-22-3p ; hsa-mir-1229-3p ; hsa-mir-320a ; hsa-mir-100-5p ; hsa-mir-9-5p ; hsa-mir-512-5p ; hsa-mir-218-5p ; hsa-mir-4276 ; hsa-mir-105-5p ; hsa-mir-7853-5p ; hsa-mir-578 ; hsa-mir-548aw ; hsa-mir-526b-5p ; hsa-mir-1468-3p ; hsa-mir-548x-5p ; hsa-mir-548g-5p ; hsa-mir-548f-5p ; hsa-mir-548aj-5p ; hsa-mir-1181 ; hsa-mir-5195-5p ; hsa-mir-4480 ; hsa-mir-577 ; hsa-mir-497-3p ; hsa-mir-1277-5p ; hsa-mir-607 ; hsa-mir-3671 ; hsa-mir-190a-3p ; hsa-mir-223-5p ; hsa-mir-511-3p ; hsa-mir-5011-5p ; hsa-let-7c-3p ; hsa-mir-486-5p ; hsa-mir-8485 ; hsa-mir-649 ; hsa-mir-335-3p ; hsa-mir-30e-3p ; hsa-mir-30d-3p ; hsa-mir-30a-3p ; hsa-mir-6882-3p ; hsa-mir-27b-5p ; hsa-mir-152-3p ; hsa-mir-148b-3p ; hsa-mir-148a-3p ; hsa-mir-556-5p ; hsa-mir-512-3p ; hsa-mir-208b-5p ; hsa-mir-208a-5p ; hsa-mir-367-5p ; hsa-mir-4639-5p ; hsa-mir-4517 ; hsa-mir-19b-3p ; hsa-mir-19a-3p ; hsa-mir-6507-3p ; hsa-mir-1264 ; hsa-mir-431-5p ; hsa-mir-561-3p ; hsa-mir-6821-5p
Nearest miRNA
hsa-let-7g/Upstream/1971435; hsa-mir-12124/Downstream/521500;
Nearest TSS
ENST00000440867/Upstream/42441; ENST00000465742/Downstream/21048;
Nearest CpG islands
None/Target, chr3-CpG: 148/Upstream/1280413, chr3-CpG: 50/Downstream/44713
Nearest cancer related gene
FOXP1(OG, No orient, 0)
Upstream sequence
ATACCACCCAAGGTCTTCACTTCAACACTGACCTTAGTTTTTGAGACAATTTTATATAATGGTTATGGTTCCTTATGACATTTCATGGTTATATTCCCAA
Downstream sequence
GGTCACTACTTAACCAAAGCTTCAAACTGGAATTACTAAATCCACCTGCTAAATAAGGACAACTTCTCAACTCTGCTGTCTGCAGTCTTTAGTGATCCTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate