Basic Information
VIS ID
TVIS30014234
Fusion event
HIV-NBR1 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr17
Cytoband
q21.31
Reference genome
GRCh37/hg19
Start
41340719/43188702 (Hg38)
End
41340719/43188702 (Hg38)
Orient
-
Location type
Intronic
Target gene
NBR1
miRNAs that regulate target gene
hsa-mir-615-3p ; hsa-mir-18a-3p ; hsa-mir-92a-3p ; hsa-mir-17-5p
Nearest miRNA
hsa-mir-1180/Upstream/364759; hsa-mir-10226/Downstream/256104;
Nearest TSS
ENST00000595228/Upstream/10766; ENST00000585505/Downstream/1212;
Nearest CpG islands
None/Target, chr17-CpG: 26/Upstream/17356, chr17-CpG: 40/Downstream/23006
Upstream sequence
taagtctttaatccaccttgagttaatttttgtataaggtgtaaggaaggggtccagtttcagttttctacatatggctagccagttttcccagcaccgt
Downstream sequence
ttattaaatagggaatcctttccccattgcctgtttcagtcTATCCAATTTCTAGATTTATTTCTCATTGTCTTTGTTGTAAGATTTGCACATTTATCAG
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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