Basic Information
VIS ID
TVIS30014237
Fusion event
HIV-DENND1B integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr1
Cytoband
q31.3
Reference genome
GRCh37/hg19
Start
197637249/197668119 (Hg38)
End
197637249/197668119 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA1K
Target gene
DENND1B
miRNAs that regulate target gene
hsa-mir-6869-5p ; hsa-mir-155-5p ; hsa-mir-4312 ; hsa-mir-532-5p ; hsa-mir-802 ; hsa-mir-365b-3p ; hsa-mir-365a-3p ; hsa-mir-195-3p
Nearest miRNA
hsa-mir-101-1/Upstream/1085638; hsa-mir-1182/Downstream/1190754;
Nearest TSS
ENST00000473358/Upstream/9769; ENST00000440885/Downstream/67410;
Nearest CpG islands
None/Target, chr1-CpG: 111/Upstream/466530, chr1-CpG: 103/Downstream/106682
Upstream sequence
GTACATACAATCCCATATTAAGATACAAATATTTATGTGTTAGCTATTTCTTAAAatacatatacatttacatacacatataACTTGTTCTCTACAAATA
Downstream sequence
TAACAACATACTATAAATATTATTTTGAAATTTTTCATCATGTTACAACAGATCATAAACAATTTCTCTAAGTCAGGGTGTATATATGTGTATGTTTTTC
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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