Basic Information
VIS ID
TVIS30014243
Fusion event
HIV-AKAP9 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr7
Cytoband
q21.2
Reference genome
GRCh37/hg19
Start
91638860/92009546 (Hg38)
End
91638860/92009546 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA7E
Target gene
AKAP9
miRNAs that regulate target gene
hsa-mir-192-5p ; hsa-mir-21-5p
Nearest miRNA
hsa-mir-10525/Upstream/16094277; hsa-mir-10399/Downstream/194469;
Nearest TSS
ENST00000635602/Upstream/35790; ENST00000484815/Downstream/31158;
Nearest CpG islands
None/Target, chr7-CpG: 39/Upstream/68512, chr7-CpG: 115/Downstream/124235
Nearest cancer related gene
AKAP9(OG, No orient, 0)
Upstream sequence
aacaattaaagaatttgaaatcatagagattttccctctctcctctcctccaaccagaaatattagactgagaccatttcacaaatgggtcttaccaact
Downstream sequence
ctcaacgaatatataattgcttaataaaataggattaaagggagagaactagggggaagaaaagaaggaaagaagaaaggtaagctagacaaaagaaaaa
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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