Basic Information
VIS ID
TVIS30014248
Fusion event
HIV-NUP93 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q13
Reference genome
GRCh37/hg19
Start
56820266/56786354 (Hg38)
End
56820266/56786354 (Hg38)
Orient
-
Location type
Intronic
Target gene
NUP93
miRNAs that regulate target gene
hsa-mir-218-5p ; hsa-mir-125b-5p ; hsa-mir-3149 ; hsa-mir-4715-3p ; hsa-mir-4763-5p ; hsa-mir-29a-5p ; hsa-mir-6727-3p ; hsa-mir-4722-3p ; hsa-mir-6872-3p ; hsa-let-7c-3p ; hsa-mir-4266 ; hsa-mir-3177-5p ; hsa-mir-3650 ; hsa-mir-4455 ; hsa-mir-6747-5p ; hsa-mir-6738-5p ; hsa-mir-5194 ; hsa-mir-3922-5p ; hsa-mir-1914-3p ; hsa-mir-6782-5p ; hsa-mir-4779 ; hsa-mir-4695-5p ; hsa-mir-4274 ; hsa-mir-624-3p ; hsa-mir-6839-3p ; hsa-mir-4507 ; hsa-mir-3940-5p ; hsa-mir-23b-5p ; hsa-mir-23a-5p ; hsa-mir-6781-3p ; hsa-mir-2682-3p ; hsa-mir-6774-5p ; hsa-mir-635 ; hsa-mir-4772-3p ; hsa-mir-4638-5p ; hsa-mir-1304-3p ; hsa-mir-6741-3p ; hsa-mir-4485-5p ; hsa-mir-6890-3p ; hsa-mir-6855-5p ; hsa-mir-3170 ; hsa-mir-7703 ; hsa-mir-6807-5p ; hsa-mir-7151-3p ; hsa-mir-5095 ; hsa-mir-193b-5p ; hsa-mir-4252 ; hsa-mir-7155-5p ; hsa-mir-4793-3p ; hsa-mir-1273g-3p ; hsa-mir-4438 ; hsa-mir-128-3p ; hsa-mir-216a-3p ; hsa-mir-27a-3p ; hsa-mir-27b-3p ; hsa-mir-3681-3p ; hsa-mir-6081 ; hsa-mir-6750-3p
Nearest miRNA
hsa-mir-1225/Upstream/540731; hsa-mir-11401/Downstream/72164;
Nearest TSS
ENST00000527434/Upstream/2898; ENST00000563437/Downstream/45161;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/55789, chr16-CpG: 80/Downstream/145468
Upstream sequence
GTTGCTggccttagggtttagtgcaatcagctcatgttatagttaagtaaaggaaggcttaactgcagttaaataactttctcaaggtcatacatctgga
Downstream sequence
aagcagtcgattttgccctaaatctggaccacctgactcctaatctgtgctGCACTGTGTCTCTGTCTGCATCTGACTCCATTTCTTTCTCTGCCAGCTT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate