Basic Information
VIS ID
TVIS30014253
Fusion event
HIV-RPGRIP1L integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr16
Cytoband
q12.2
Reference genome
GRCh37/hg19
Start
53671909/53637997 (Hg38)
End
53671909/53637997 (Hg38)
Orient
+
Location type
Intronic
Target gene
RPGRIP1L
miRNAs that regulate target gene
hsa-mir-375 ; hsa-mir-192-5p ; hsa-mir-1229-3p
Nearest miRNA
hsa-mir-1225/Upstream/2895620; hsa-mir-11401/Downstream/2607523;
Nearest TSS
ENST00000527434/Upstream/133586; ENST00000570395/Downstream/377;
Nearest CpG islands
None/Target, chr16-CpG: 29/Upstream/134224, chr16-CpG: 51/Downstream/65708
Upstream sequence
TCACATTTTATAGCATTATTGCTGGAACAGTTGAATAATAAAGCATGTAAATTTGAGACTTAAATATACAGATATGTAATATGTATGAGACTCAGAAAAC
Downstream sequence
AACCACTTCAATTTGTACAAATGATAATATATAGATAAATGGAAATCTGAATATGTACTAAGAATAAAAAATGTATTAATCTCAAAATGAATTTTACATT
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
Curate