Basic Information
VIS ID
TVIS30014254
Fusion event
HIV-GORASP2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr2
Cytoband
q31.1
Reference genome
GRCh37/hg19
Start
171811130/170954620 (Hg38)
End
171811130/170954620 (Hg38)
Orient
-
Location type
Intronic
Fragile sites / regions
FRA2G
Target gene
GORASP2
miRNAs that regulate target gene
hsa-mir-197-3p ; hsa-mir-34a-5p ; hsa-mir-877-5p ; hsa-mir-320a ; hsa-mir-10a-5p ; hsa-mir-24-3p ; hsa-let-7c-5p ; hsa-let-7a-5p
Nearest miRNA
hsa-mir-128-1/Upstream/2371602; hsa-mir-10b/Downstream/4213013;
Nearest TSS
ENST00000437798/Upstream/802; ENST00000495925/Downstream/100509;
Nearest CpG islands
None/Target, chr2-CpG: 135/Upstream/24954, chr2-CpG: 69/Downstream/18780
Upstream sequence
AAGAAGggagtgcatgttcagggcaacttgaatctatgctcttgggttacCCGCCCCCCCCAAAAAAAACACCTCAAAGAAATACAAGCTGTGATAGATA
Downstream sequence
ACAACGTTAAGAAAAAAATGTTTTTATAGCCTAGGATGTGGCATTGGATATGGTTATTTGCATCGAATACCTACACGCCCATTTGAGGAAGGAAAGAAAA
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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