Basic Information
VIS ID
TVIS30014256
Fusion event
HIV-UBR2 integration
Validated
Yes
Detection method
invPCR
Data source
download(RID)
Sample type
PBMC
Disease
HIV-infected disease (HID)
Quality evaluation
Normal
Reported year
2007
PubMed ID
17262715
Virus Sequence
Virus name
HIV
Reference genome
Not given
Host Sequence
Chromosome
chr6
Cytoband
p21.1
Reference genome
GRCh37/hg19
Start
42550847/42583109 (Hg38)
End
42550847/42583109 (Hg38)
Orient
+
Location type
Intronic
Fragile sites / regions
FRA6H
Target gene
UBR2
miRNAs that regulate target gene
hsa-mir-335-5p ; hsa-mir-5580-3p
Nearest miRNA
hsa-mir-10398/Upstream/849499; hsa-mir-10524/Downstream/851433;
Nearest TSS
ENST00000381078/Upstream/19047; ENST00000614467/Downstream/139465;
Nearest CpG islands
None/Target, chr6-CpG: 120/Upstream/18555, chr6-CpG: 71/Downstream/144018
Upstream sequence
ttcattatctttattcacttttggagttctttattctgaatacaagtccttcgtcagactcattttgtgactattttctcctaggctgtggcttgtttct
Downstream sequence
atggtggcttttgatgacagaagtttttaattttaatgttcaatttaccactttttttcatgattattgttcttgtgtccagtaaatctctgccttctct
Reference
Ikeda, T., et al. Recurrent HIV-1 integration at the BACH2 locus in resting CD4+ T cell populations during effective highly active antiretroviral therapy. J Infect Dis,2007, 195(5): 716-725.
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